SCHEMBL6156491

SCHEMBL6156491

CNC(=O)C(=NOC)c1ccccc1CON=C(C)[C@@H]1C[C@@]1(C)c1ccc(F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156932 1.00 HIF1A (0.35) HIF1A
SCHEMBL6155943 0.92 HIF1A (0.44) HIF1A
SCHEMBL6158790 0.92 HIF1A (0.44) HIF1A
SCHEMBL6157921 0.91 HIF1A (0.36) HIF1A
SCHEMBL6156662 0.90 HIF1A (0.35) HIF1A
SCHEMBL6156663 0.90 HIF1A (0.35) HIF1A
SCHEMBL6157929 0.88 HIF1A (0.36) HIF1A
SCHEMBL6156120 0.88 HIF1A (0.36) HIF1A
SCHEMBL6158217 0.81
SCHEMBL23971831 0.78 HIF1A (0.43) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286955-B1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2005-02-02 EP claimed
EP-1286955-B1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2005-02-02 EP disclosed
US-6348627-B1 CONTROLLING PHYTOPATHOGENIC FUNGI DOW AGROSCIENCES LLC 2002-02-19 US disclosed
US-6303818-B1 Unsaturated oxime ethers and their use as fungicides DOW AGROSCIENCES LLC 2001-10-16 US disclosed