SCHEMBL6156663

SCHEMBL6156663

CON=C(C(N)=O)c1ccccc1CON=C(C)C1CC1(C)c1ccc(F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.35
HNF4A P41235 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
PARP14 Q460N5 1/20 0.30
PARP10 Q53GL7 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156662 1.00 HIF1A (0.35) HIF1AHNF4AHTR2AHTR2CHTR2B
SCHEMBL6157921 0.92 HIF1A (0.36) HIF1AHNF4A
SCHEMBL6158790 0.92 HIF1A (0.44) HIF1AHNF4A
SCHEMBL6155943 0.92 HIF1A (0.44) HIF1AHNF4A
SCHEMBL6156932 0.90 HIF1A (0.35) HIF1A
SCHEMBL6156491 0.90 HIF1A (0.35) HIF1A
SCHEMBL6156949 0.84 HIF1A (0.38) HIF1A
SCHEMBL6156942 0.84 HIF1A (0.38) HIF1A
SCHEMBL7152976 0.83 HIF1A (0.35) HIF1A
SCHEMBL7152978 0.83 HIF1A (0.35) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286955-B1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2005-02-02 EP claimed