Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158168 | 1.00 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL7700157 | 1.00 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL6155978 | 1.00 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL6156945 | 1.00 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL6156654 | 0.91 | HIF1A (0.39) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL6156658 | 0.91 | HIF1A (0.39) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL6155347 | 0.91 | HIF1A (0.38) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL6155346 | 0.91 | HIF1A (0.38) | HIF1APTGS2NR1H4LMNAPPARG | |
| SCHEMBL7707860 | 0.89 | HIF1A (0.48) | HIF1APTGS2LMNAALDH1A1 | |
| SCHEMBL6156049 | 0.89 | HIF1A (0.48) | HIF1APTGS2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | disclosed |