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SCHEMBL7707860

SCHEMBL7707860

CO/N=C(/C(=O)OC)c1ccccc1CO/N=C(\C)[C@@H]1C[C@H]1c1c(F)cccc1F

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 8/20 0.48
▸ PKM P14618 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ GPR88 Q9GZN0 1/20 0.31
▸ PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156049 1.00 HIF1A (0.48) HIF1APKMKDM4EALDH1A1LMNA
SCHEMBL6156045 1.00 HIF1A (0.48) HIF1APKMKDM4EALDH1A1LMNA
SCHEMBL6158177 0.91 HIF1A (0.38) HIF1AMAPTL3MBTL1GPR88
SCHEMBL7035838 0.91 HIF1A (0.38) HIF1AMAPTL3MBTL1GPR88
SCHEMBL6156945 0.89 HIF1A (0.48) HIF1AALDH1A1LMNAPTGS2
SCHEMBL6158168 0.89 HIF1A (0.48) HIF1AALDH1A1LMNAPTGS2
SCHEMBL6155978 0.89 HIF1A (0.48) HIF1AALDH1A1LMNAPTGS2
SCHEMBL6156508 0.89 HIF1A (0.48) HIF1AALDH1A1LMNAPTGS2
SCHEMBL7700157 0.89 HIF1A (0.48) HIF1AALDH1A1LMNAPTGS2
SCHEMBL6226964 0.86 HIF1A (0.50) HIF1AALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348627-B1 CONTROLLING PHYTOPATHOGENIC FUNGI DOW AGROSCIENCES LLC 2002-02-19 — — US disclosed