SCHEMBL6156635

SCHEMBL6156635

COc1ccc(CCNS(C)(=O)=O)cc1OC

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.75
CA12 O43570 2/20 0.75
CA1 P00915 2/20 0.75
CA2 P00918 2/20 0.75
CA9 Q16790 2/20 0.75
CA5A P35218 1/20 0.75
CA14 Q9ULX7 1/20 0.75
HTT P42858 2/20 0.68
ALDH1A1 P00352 3/20 0.64
POLB P06746 1/20 0.63
ATM Q13315 1/20 0.63
KMT2A Q03164 1/20 0.59
MAPT P10636 1/20 0.56
LMNA P02545 1/20 0.56
PDE4B Q07343 1/20 0.55
PDE4C Q08493 1/20 0.55
PDE4D Q08499 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14009914 0.86 SMN1; SMN2 (0.73) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL2592710 0.84 CA12 (0.71) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL8567718 0.84 SMN1; SMN2 (0.55) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL7271170 0.83 SMN1; SMN2 (0.68) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL5960056 0.81 HTT (1.00) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL5960103 0.80 ALDH1A1 (0.79) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL7435099 0.79 ATM (0.76) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL5960089 0.79 HTT (0.64) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL508554 0.79 ALDH1A1 (0.77) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL5960050 0.79 ALDH1A1 (0.77) SMN1; SMN2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9081142-B2 Photosensitive resin composition for a color filter and uses thereof CHI MEI CORPORATION (TW) 2015-07-14 US disclosed
US-9081142-B2 Photosensitive resin composition for a color filter and uses thereof CHI MEI CORPORATION (TW) 2015-07-14 US disclosed
US-20140346416-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF CHI MEI CORPORATION (TW) 2014-11-27 US disclosed
US-20140346416-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF CHI MEI CORPORATION (TW) 2014-11-27 US disclosed
EP-1517680-A1 BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA Astrazeneca AB (SE) 2005-03-30 EP disclosed
EP-1497288-A1 NOVEL ESTER HYDROXY-SUBSTITUTED NITROGEN HETEROCYCLES AS ANTAGONISTS OF THE MUSCARINIC M3 RECEPTOR, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2005-01-19 EP disclosed
WO-2004000295-A1 BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA ASTRAZENECA AB (SE) 2003-12-31 WO disclosed
WO-2003087096-A1 NOVEL ESTER HYDROXY-SUBSTITUTED NITROGEN HETEROCYCLES AS ANTAGONISTS OF THE MUSCARINIC M3 RECEPTOR, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2003-10-23 WO disclosed