Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.56 |
| ▸ | CTSK | P43235 | 9/20 | 0.56 |
| ▸ | CTSB | P07858 | 4/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438999 | 0.90 | CTSS (0.59) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL2859101 | 0.89 | CTSS (0.61) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL2856700 | 0.89 | CTSS (0.61) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL2856693 | 0.89 | CTSS (0.61) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL6155054 | 0.85 | CTSS (0.52) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL1273042 | 0.82 | CTSS (0.64) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL12122453 | 0.82 | CTSS (0.64) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL14803767 | 0.80 | PPARG (0.53) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL20045974 | 0.80 | PPARG (0.53) | CTSSCTSKCTSBSCN9ACTSL | |
| SCHEMBL12643835 | 0.79 | CTSS (0.52) | CTSSCTSKCTSBSCN9ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004046091-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |