Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154316 | 0.99 | HMGCR (0.38) | HMGCR | |
| SCHEMBL6156164 | 0.92 | — | — | |
| SCHEMBL6156247 | 0.86 | — | — | |
| SCHEMBL6154762 | 0.79 | HMGCR (0.40) | HMGCR | |
| SCHEMBL6879551 | 0.76 | HMGCR (0.36) | HMGCR | |
| SCHEMBL6155756 | 0.76 | HMGCR (0.36) | HMGCR | |
| SCHEMBL6155888 | 0.76 | HSP90AA1 (0.38) | HMGCR | |
| SCHEMBL6881436 | 0.75 | HMGCR (0.37) | HMGCR | |
| SCHEMBL6884487 | 0.75 | HMGCR (0.35) | HMGCR | |
| SCHEMBL6884494 | 0.74 | HMGCR (0.35) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |