SCHEMBL6156864

SCHEMBL6156864

CCCC1CCc2cc(O)ccc2C1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.57
OPRK1 P41145 1/20 0.54
DRD2 P14416 10/20 0.51
DRD3 P35462 10/20 0.51
DRD4 P21917 6/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
HTR1A P08908 1/20 0.51
ADRB2 P07550 1/20 0.51
CYP2D6 P10635 1/20 0.51
CASP1 P29466 1/20 0.51
LMNA P02545 2/20 0.50
CYP26A1 O43174 1/20 0.50
FYN P06241 1/20 0.50
MAPT P10636 1/20 0.50
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11146141 0.88 CYP26A1 (0.49) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL630379 0.87 CYP19A1 (0.60) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL4621043 0.84 CYP19A1 (0.54) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL5582712 0.83 CYP19A1 (0.53) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL4621898 0.83 CYP19A1 (0.53) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL5661239 0.83 CYP19A1 (0.56) CYP19A1OPRK1DRD2DRD3DRD4
Hydrochloric Acid SCHEMBL4622834 0.82 CYP19A1 (0.52) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL5661590 0.81 CYP19A1 (0.61) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL4623601 0.81 DRD2 (0.57) CYP19A1OPRK1DRD2DRD3DRD4
SCHEMBL4621095 0.81 CYP19A1 (0.51) CYP19A1OPRK1DRD2DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191008-B1 COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DAINIPPON INK & CHEMICALS (JP) 2005-02-09 EP disclosed
US-6746728-B1 SUPERIOR LIQUID CRYSTALLINITY AND CO-SOLUBILITY WITH CURRENTLY USED LIQUID CRYSTAL COMPOUNDS; TEMPERATURE RANGE OVER WHICH LIQUID CRYSTALLINITY IS SHOWN IS BROAD; THRESHOLD VOLTAGE IS LOW; CAPABLE OF HIGH SPEED RESPONSE DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-06-08 US disclosed
EP-1191008-A1 COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-03-27 EP disclosed