Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158197 | 0.86 | SPHK1 (0.35) | HTR1DHTR1BSPHK1 | |
| SCHEMBL14228674 | 0.83 | SPHK1 (0.33) | HTR1DHTR1BSPHK1 | |
| SCHEMBL6157524 | 0.79 | SPHK1 (0.35) | HTR1DHTR1BSPHK1 | |
| SCHEMBL10896984 | 0.77 | SPHK1 (0.43) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL7782680 | 0.75 | ALDH1A1 (0.39) | HTR1DHTR1BALDH1A1MAPT | |
| SCHEMBL7796703 | 0.75 | SPHK1 (0.46) | ALDH1A1SPHK1 | |
| SCHEMBL9433023 | 0.73 | SPHK1 (0.39) | SPHK1 | |
| SCHEMBL14525542 | 0.73 | ALDH1A1 (0.39) | HTR1DHTR1BMEN1ALDH1A1MAPT | |
| SCHEMBL6156737 | 0.71 | HTR1D (0.51) | HTR1DHTR1BSPHK1 | |
| SCHEMBL24225349 | 0.70 | CYP3A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191008-B1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6746728-B1 | SUPERIOR LIQUID CRYSTALLINITY AND CO-SOLUBILITY WITH CURRENTLY USED LIQUID CRYSTAL COMPOUNDS; TEMPERATURE RANGE OVER WHICH LIQUID CRYSTALLINITY IS SHOWN IS BROAD; THRESHOLD VOLTAGE IS LOW; CAPABLE OF HIGH SPEED RESPONSE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1191008-A1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-03-27 | — | — | EP | disclosed |