Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156949 | 0.93 | HIF1A (0.38) | HIF1ASMN1; SMN2MAPTLMNAMETAP2 | |
| SCHEMBL6156942 | 0.93 | HIF1A (0.38) | HIF1ASMN1; SMN2MAPTLMNAMETAP2 | |
| SCHEMBL6156221 | 0.91 | HIF1A (0.52) | HIF1AF10SMN1; SMN2MAPTC5AR1 | |
| SCHEMBL7705191 | 0.91 | HIF1A (0.52) | HIF1AF10SMN1; SMN2MAPTC5AR1 | |
| SCHEMBL6155881 | 0.83 | HIF1A (0.48) | HIF1ASMN1; SMN2MAPTLMNA | |
| SCHEMBL6155883 | 0.83 | HIF1A (0.48) | HIF1ASMN1; SMN2MAPTLMNA | |
| SCHEMBL6155877 | 0.83 | HIF1A (0.48) | HIF1ASMN1; SMN2MAPTLMNA | |
| SCHEMBL6156662 | 0.81 | HIF1A (0.35) | HIF1A | |
| SCHEMBL6156663 | 0.81 | HIF1A (0.35) | HIF1A | |
| SCHEMBL6157929 | 0.80 | HIF1A (0.36) | HIF1ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | disclosed |