Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphocholine SCHEMBL9613934 | 0.94 | LMNA (0.52) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL14742786 | 0.94 | LMNA (0.52) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL8011 | 0.94 | LMNA (0.52) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL8584618 | 0.92 | LMNA (0.50) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL16038749 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL5143800 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL9095327 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL18662890 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL28621201 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAADRA1AAKT1ESR1 | |
| Phosphocholine SCHEMBL8461139 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAADRA1AAKT1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989138-B1 | Ocular lens material and process for producing the same | MENICON CO LTD (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6346594-B1 | SILICONE POLYMER FOR INTRAOCULAR LENSES WITH AMINE GROUPS | MENICON CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-0989138-A2 | Ocular lens material and process for producing the same | Menicon Co., Ltd. (JP) | 2000-03-29 | — | — | EP | disclosed |