Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGAV | P06756 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680922 | 0.86 | ACE (0.63) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL8300245 | 0.83 | ACE (0.59) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL17933020 | 0.80 | ACE (0.60) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL10099987 | 0.80 | ACE (0.60) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL13286814 | 0.78 | ACE (0.58) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL15565481 | 0.78 | ACE (0.58) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL13227703 | 0.78 | PTPN1 (0.63) | ACEITGB3ITGA2BITGB1CTSS | |
| SCHEMBL18089317 | 0.78 | ACE (0.53) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL9956403 | 0.77 | ACE (0.63) | ACEITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL14638965 | 0.77 | ACE (0.63) | ACEITGB3ITGAVITGA2BITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004046091-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |