Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.41 |
| ▸ | NPY1R | P25929 | 9/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.41 |
| ▸ | NPY2R | P49146 | 5/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161987 | 1.00 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL30792487 | 0.86 | NOD1 (0.51) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL6376396 | 0.86 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RNOD1 | |
| SCHEMBL3194515 | 0.83 | NOD1 (0.48) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL13482067 | 0.83 | NOD1 (0.48) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL16468933 | 0.83 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL2189528 | 0.82 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9450569 | 0.82 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9450578 | 0.82 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL23286096 | 0.82 | NOD1 (0.50) | NPY4RNPY1RNPY5RNPY2RSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504094-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | Pharmacia Corporation (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003095475-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | PHARMACIA CORPORATION (US) | 2003-11-20 | — | — | WO | disclosed |