SCHEMBL6157627

SCHEMBL6157627

Nc1c(C(=O)O)c(C(=O)O)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.62
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
MAPK1 P28482 5/20 0.62
THRB P10828 3/20 0.62
MCL1 Q07820 3/20 0.62
PKM P14618 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
KDM4E B2RXH2 2/20 0.62
USP2 O75604 1/20 0.62
ALDH1A1 P00352 6/20 0.59
LMNA P02545 3/20 0.59
POLB P06746 3/20 0.59
RECQL P46063 1/20 0.59
GRK6 P43250 1/20 0.53
MAOA P21397 3/20 0.52
ADORA2A P29274 3/20 0.52
CSNK1A1 P48729 2/20 0.52
CSNK1D P48730 2/20 0.52
CSNK1G1 Q9HCP0 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27691621 0.98 MAPT (0.60) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL4704882 0.90 MAPT (0.53) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL353760 0.90 MAPT (0.53) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL29450065 0.90 MAPT (0.53) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL27823259 0.90 MAPT (0.53) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL11347778 0.88 MAPT (0.54) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL5617186 0.84 GRK6 (0.62) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL9612618 0.82 MAPT (0.54) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL11413282 0.81 MAPT (0.55) MAPTKMT2AMEN1MAPK1THRB
SCHEMBL2361188 0.81 KMT2A (0.45) MAPTKMT2AMEN1MAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4682983-A Transfer sheet for the thermal dry impression of cellulose fibers SICPA HOLDING S.A. (CH) 1987-07-28 US claimed
EP-0099333-B1 TRANSFER SHEETS FOR THE THERMAL DRY-PRINTING OF CELLULOSIC FIBRES SICPA HOLDING S.A. (CH) 1986-09-24 EP claimed
US-4369038-A Transfer-printing paper, its manufacture and uses CIBA-GEIGY LTD. (CH) 1983-01-18 US claimed
EP-2334738-B1 N-ALKOXYLATED 2,3-ANTHRAQUINONEDICARBOXIMIDES FOR POLYMER COLORATION, PREPARATION AND USE CLARIANT INT LTD (CH) 2013-07-03 EP disclosed
US-8466189-B2 N-alkoxylated 2,3-anthraquinonedicarboximides for polymer coloration, preparation and use CLARIANT (PRODUKTE) DEUTSCHLAND GMBH (DE) 2013-06-18 US disclosed
US-8466189-B2 N-alkoxylated 2,3-anthraquinonedicarboximides for polymer coloration, preparation and use CLARIANT (PRODUKTE) DEUTSCHLAND GMBH (DE) 2013-06-18 US disclosed
US-20110218276-A1 N-ALKOXYLATED 2,3-ANTHRAQUINONEDICARBOXIMIDES FOR POLYMER COLORATION, PREPARATION AND USE DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-09-08 US disclosed
US-20110218276-A1 N-ALKOXYLATED 2,3-ANTHRAQUINONEDICARBOXIMIDES FOR POLYMER COLORATION, PREPARATION AND USE DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-09-08 US disclosed
WO-2010023151-A2 DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-03-04 WO disclosed
EP-0962831-B1 Toner composition for use in textile printing XEIKON INT NV (BE) 2005-02-02 EP disclosed
JP-2000029238-A TONER COMPOSITION FOR USE IN TEXTILE PRINTING AGFA GEVAERT NV 2000-01-28 JP disclosed
US-6007955-A Toner composition for use in textile printing AGFA-GEVAERT, N.V. (BE) 1999-12-28 US disclosed
EP-0962831-A1 Toner composition for use in textile printing AGFA-GEVAERT N.V. (BE) 1999-12-08 EP disclosed
WO-1996016015-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1996-05-30 WO disclosed
US-4682983-A Transfer sheet for the thermal dry impression of cellulose fibers SICPA HOLDING S.A. (CH) 1987-07-28 US disclosed
US-4369038-A Transfer-printing paper, its manufacture and uses CIBA-GEIGY LTD. (CH) 1983-01-18 US disclosed
US-4001335-A PRODUCTION OF 3-MONOCHLORO-2,4,5-TRIALKYLBENZOPHENONES AND 3,6-DICHLORO-2,4,5-TRIALKYLBENZOPHENONES BASF AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218276-A1 N-ALKOXYLATED 2,3-ANTHRAQUINONEDICARBOXIMIDES FOR POLYMER COLORATION, PREPARATION AND USE ANTXR2, SDHB, NQO2 MAPT 2914/4885KMT2A 898/4885MEN1 1553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.