Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14828741 | 0.81 | MEN1 (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8136050 | 0.77 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL13532539 | 0.77 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14074603 | 0.77 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7804741 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1POLBLMNAKDM4E | |
| SCHEMBL7802817 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1POLBLMNAKDM4E | |
| SCHEMBL14827641 | 0.74 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15679077 | 0.73 | MEN1 (0.73) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL12948551 | 0.72 | SMN1; SMN2 (0.63) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16508660 | 0.70 | MEN1 (0.73) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948563-B1 | MODIFYING AGENTS FOR POLYOLEFINS | MINNESOTA MINING & MFG (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6096811-A | COMPOSITION COMPRISING POLYOLEFIN, ANTIOXIDANT, NUCLEATING OR CLARIFYING AGENT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-01 | — | — | US | disclosed |