Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14664114 | 0.85 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14828741 | 0.83 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12948551 | 0.77 | SMN1; SMN2 (0.63) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14663979 | 0.76 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14828726 | 0.74 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6158083 | 0.74 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8136050 | 0.73 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20759128 | 0.73 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11798566 | 0.73 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19678572 | 0.73 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735398-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | HAVCR2, MAVS, GTF3C1 | MEN1 4812/4885KMT2A 3866/4885SMN1; SMN2 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.