Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739556 | 0.95 | ESR1 (0.59) | ESR1ESR2AKR1C1HSP90AA1DHFR | |
| SCHEMBL29378579 | 0.90 | ESR1 (0.69) | ESR1ESR2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL515744 | 0.90 | ESR1 (0.69) | ESR1ESR2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL30806212 | 0.90 | ESR1 (0.69) | ESR1ESR2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL2029878 | 0.90 | AKR1C1 (0.57) | ESR1ESR2AKR1C1HSP90AA1DHFR | |
| SCHEMBL29967186 | 0.90 | AKR1C1 (0.57) | ESR1ESR2AKR1C1HSP90AA1DHFR | |
| SCHEMBL18386004 | 0.85 | ESR1 (0.63) | ESR1ESR2L3MBTL1ALDH1A1MEN1 | |
| Phenol SCHEMBL3001011 | 0.84 | ESR2 (0.61) | ESR1ESR2TYMSL3MBTL1ALDH1A1 | |
| SCHEMBL10696087 | 0.83 | ESR1 (0.64) | ESR1ESR2TYMSL3MBTL1ALDH1A1 | |
| SCHEMBL9769550 | 0.83 | ESR1 (0.64) | ESR1ESR2TYMSL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204693-B1 | POLYESTERCARBONATE COMPRISING RESIDUES OF BRANCHED DIACIDS | GEN ELECTRIC (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1204693-A1 | POLYESTERCARBONATE COMPRISING RESIDUES OF BRANCHED DIACIDS | GENERAL ELECTRIC COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009222-A1 | POLYESTERCARBONATE COMPRISING RESIDUES OF BRANCHED DIACIDS | GENERAL ELECTRIC COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |