SCHEMBL9769550

SCHEMBL9769550

Cc1cc(C2(c3cc(C)c(O)c(C)c3)c3ccccc3-c3ccccc32)cc(C)c1O.Oc1ccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.64
ESR2 Q92731 2/20 0.64
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
LMNA P02545 5/20 0.47
MAPT P10636 5/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
OPRK1 P41145 1/20 0.47
GPR55 Q9Y2T6 5/20 0.43
CNR1 P21554 3/20 0.43
HTT P42858 1/20 0.43
GPR35 Q9HC97 1/20 0.43
POLB P06746 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CHRM2 P08172 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10696087 1.00 ESR1 (0.64) ESR1ESR2MEN1KMT2ALMNA
Phenol SCHEMBL3001011 0.92 ESR2 (0.61) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL515744 0.92 ESR1 (0.69) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL30806212 0.92 ESR1 (0.69) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL29378579 0.92 ESR1 (0.69) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL18386004 0.87 ESR1 (0.63) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL17399575 0.86 ESR1 (0.88) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL10697013 0.86 ESR1 (0.88) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL6208231 0.86 ESR1 (0.88) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL2564189 0.86 ESR1 (0.51) ESR1ESR2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049169-A Oxygen, nitrogen selectivity NIPPON STEEL CORPORATION (JP) 1991-09-17 US disclosed