SCHEMBL6158089

SCHEMBL6158089

CCc1c(O)cccc1Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.52
BCL2L1 Q07817 1/20 0.52
KEAP1 Q14145 1/20 0.48
ALOX5 P09917 1/20 0.46
HSPA5 P11021 1/20 0.43
MEN1 O00255 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
KMT2A Q03164 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ELANE P08246 1/20 0.41
CTSG P08311 1/20 0.41
PKM P14618 1/20 0.41
IDH1 O75874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL29037547 0.88 BCL2L1 (0.41) BCL2BCL2L1KEAP1ALOX5GABRA1
SCHEMBL11213121 0.86 BCL2 (0.57) BCL2BCL2L1KEAP1ALOX5HSPA5
SCHEMBL30957380 0.86 BCL2 (0.57) BCL2BCL2L1KEAP1ALOX5HSPA5
SCHEMBL1838403 0.86 BCL2 (0.57) BCL2BCL2L1KEAP1ALOX5HSPA5
SCHEMBL10483677 0.86 BCL2 (0.46) BCL2BCL2L1KEAP1ALOX5HSPA5
SCHEMBL10599555 0.86 TP53 (0.50) BCL2BCL2L1TP53HTR2A
SCHEMBL6158092 0.85 HSP90AA1 (0.50) BCL2BCL2L1KEAP1ALOX5HSPA5
Fluoride SCHEMBL27996603 0.85 BCL2 (0.55) BCL2BCL2L1KEAP1ALOX5HSPA5
SCHEMBL9845810 0.83 BCL2L1 (0.46) BCL2BCL2L1KEAP1ALOX5HPGD
SCHEMBL11213120 0.82 HSPA5 (0.54) BCL2BCL2L1KEAP1ALOX5HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1500097-A2 COATING FORMULATIONS FOR LIMITED PLAY DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2005-01-26 EP disclosed
WO-2003089528-A2 COATING FORMULATIONS FOR DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2003-10-30 WO disclosed