SCHEMBL9845810

SCHEMBL9845810

CCCCc1c(O)cccc1Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 3/20 0.46
BCL2 P10415 1/20 0.46
BID P55957 3/20 0.44
MCL1 Q07820 3/20 0.44
KAT8 Q9H7Z6 3/20 0.44
BAK1 Q16611 2/20 0.44
EP300 Q09472 2/20 0.44
KAT5 Q92993 2/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
KAT2A Q92830 1/20 0.44
KAT2B Q92831 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
HTT P42858 2/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
RAB9A P51151 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KEAP1 Q14145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11331296 0.94 BID (0.52) BCL2L1BIDMCL1KAT8BAK1
SCHEMBL11683178 0.87 BCL2 (0.46) BCL2L1BCL2HTTNPC1HPGD
SCHEMBL9845811 0.87 HSP90AA1 (0.49) BCL2L1BIDMCL1KAT8BAK1
SCHEMBL8095518 0.85 TLR8 (0.44) HTTLMNALDHALDHB
Phenol SCHEMBL28085339 0.84 DRD2 (0.43) BCL2L1BCL2BIDMCL1KAT8
SCHEMBL29138369 0.84 KAT8 (0.49) BCL2L1BIDMCL1KAT8BAK1
SCHEMBL6158089 0.83 BCL2 (0.52) BCL2L1BCL2HPGDKEAP1ALOX5
SCHEMBL9498610 0.83 BCL2L1 (0.52) BCL2L1BCL2BIDMCL1BAK1
SCHEMBL162389 0.83 BID (0.51) BCL2L1BIDMCL1KAT8BAK1
SCHEMBL30468817 0.83 BID (0.51) BCL2L1BIDMCL1KAT8BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0406826-A1 Lubricant composition CIBA-GEIGY AG (CH) 1991-01-09 EP disclosed