Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 20/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | HTR2B | P41595 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157127 | 0.90 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6157306 | 0.86 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6157795 | 0.86 | HTR7 (0.80) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6161449 | 0.84 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6160848 | 0.84 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6158853 | 0.83 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL7664123 | 0.83 | HTR7 (0.82) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6159368 | 0.83 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL7612489 | 0.82 | HTR7 (0.69) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6421219 | 0.82 | HTR7 (0.78) | HTR7HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937715-B1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6355642-B1 | PSYCHOLOGICAL DISORDERS AND BRAIN DISORDERS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0937715-A1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |