Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157463 | 1.00 | TSHR (0.55) | TSHRLMNAACE2ALDH1A1CYP2D6 | |
| SCHEMBL3365945 | 1.00 | TSHR (0.55) | TSHRLMNAACE2ALDH1A1CYP2D6 | |
| SCHEMBL3367058 | 1.00 | TSHR (0.55) | TSHRLMNAACE2ALDH1A1CYP2D6 | |
| SCHEMBL1657135 | 0.97 | TSHR (0.57) | TSHRLMNAACE2ALDH1A1CYP2D6 | |
| SCHEMBL33385 | 0.92 | TSHR (0.57) | TSHRLMNAACE2ALDH1A1BLM | |
| SCHEMBL9968737 | 0.92 | TSHR (0.57) | TSHRLMNAACE2ALDH1A1BLM | |
| SCHEMBL6518338 | 0.90 | TSHR (0.55) | TSHRLMNAACE2ALDH1A1BLM | |
| SCHEMBL11570599 | 0.90 | TSHR (0.55) | TSHRLMNAACE2ALDH1A1BLM | |
| Sulfuric Acid SCHEMBL7744445 | 0.89 | TSHR (0.44) | TSHRLMNAACE2ALDH1A1CYP2D6 | |
| Sulfuric Acid SCHEMBL6157041 | 0.89 | TSHR (0.44) | TSHRLMNAACE2ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924300-B2 | Oxyiminoalkanoic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| EP-1023426-B1 | LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | PROCTER & GAMBLE (US) | 2005-02-09 | — | — | EP | disclosed |
| CN-1187036-C | Personal cleansing compositions comprising mid-chain branched surfactants | PROCTER & GAMBLE (US) | 2005-02-02 | — | — | CN | disclosed |
| EP-1023431-B1 | HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | PROCTER & GAMBLE (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1077957-B1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-1428531-A1 | Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-20030186985-A1 | Oxyiminoalkanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6495581-B1 | DRUG FOR TREATING DIABETES MELLITUS, HYPERLIPEMIA, IMPAIRED GLUCOSE TOLERANCE, ARTERIAL SCLEROSIS AND IMPROVING INSULIN RESISTANCE, INFLAMMATORY DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-6335312-B1 | BRANCHED C10-18 ALKYL ENDCAPPED ETHYLENE OXIDE-PROPYLENE OXIDE POLYETHERS TERMINATED WITH A HYDROXY GROUP THAT IS OPTIONALLY SULFATED | THE PROCTER & GAMBLE COMPANY | 2002-01-01 | — | — | US | disclosed |
| US-6281181-B1 | Light-duty liquid or gel dishwashing detergent compositions comprising mid-chain branched surfactants | THE PROCTER & GAMBLE COMPANY | 2001-08-28 | — | — | US | disclosed |
| WO-1999019449-A1 | HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019451-A1 | NON-AQUEOUS LIQUID DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019448-A1 | HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019439-A1 | LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019435-A1 | GRANULAR DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019450-A1 | AQUEOUS AND NON-AQUEOUS HEAVY DUTY LIQUID DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019440-A1 | LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019434-A1 | GRANULAR DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999018929-A1 | PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999018928-A1 | PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186985-A1 | Oxyiminoalkanoic acid derivatives | GPR119, IRS1, CPT1A | TSHR 1797/4885LMNA 2628/4885ACE2 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.