Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6161078 | 0.99 | KDM4E (0.37) | KDM4ETSHRLMNAHPGDMAPK1 | |
| SCHEMBL6157935 | 0.94 | AURKA (0.38) | KDM4ETSHRMAPK1MEN1KMT2A | |
| SCHEMBL6158156 | 0.94 | KMT2A (0.40) | KDM4ETSHRLMNAHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL7164270 | 0.93 | MEN1 (0.38) | KDM4ETSHRMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6157511 | 0.93 | KMT2A (0.39) | KDM4ETSHRLMNAHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL6159358 | 0.91 | KDM4E (0.37) | KDM4ETSHRLMNAHPGDMAPK1 | |
| SCHEMBL7838006 | 0.91 | AURKA (0.36) | KDM4EHPGDMAPK1MEN1KMT2A | |
| SCHEMBL7836074 | 0.90 | MEN1 (0.35) | ADRA2AADRA2BADRA2CKCNH3MEN1 | |
| Hydrochloric Acid SCHEMBL6158861 | 0.90 | AURKA (0.36) | KDM4EHPGDMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6159137 | 0.89 | MEN1 (0.34) | KDM4ETSHRLMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2005-10-26 | — | — | EP | claimed |
| CN-1159312-C | Novel poyrimidine derivatives and process for preparation thereof | ������������ʽ���� | 2004-07-28 | — | — | CN | claimed |
| US-6545008-B1 | Inhibitory activity against gastric acid secretion | YUHAN CORPORATION (KR) | 2003-04-08 | — | — | US | claimed |
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |