Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6158861 | 0.99 | AURKA (0.36) | AURKAKMT2AMAPTMEN1KDM4E | |
| SCHEMBL7835165 | 0.94 | AURKA (0.36) | AURKAKMT2AMAPTMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL6162784 | 0.93 | AURKA (0.35) | AURKAKMT2AMAPTMEN1KDM4E | |
| SCHEMBL6157935 | 0.92 | AURKA (0.38) | AURKAKMT2AMAPTMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL7164270 | 0.92 | MEN1 (0.38) | AURKAKMT2AMAPTMEN1KDM4E | |
| SCHEMBL7836074 | 0.91 | MEN1 (0.35) | AURKAKMT2AMAPTMEN1APP | |
| SCHEMBL6158484 | 0.91 | KDM4E (0.35) | AURKAKMT2AMEN1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6159137 | 0.90 | MEN1 (0.34) | AURKAKMT2AMEN1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6161078 | 0.90 | KDM4E (0.37) | KMT2AMEN1KDM4EHPGDMAPK1 | |
| SCHEMBL7823784 | 0.89 | KMT2A (0.37) | AURKAKMT2AMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |