Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159666 | 0.99 | KMT2A (0.39) | KMT2AMEN1BLMADRA2AADRA2B | |
| SCHEMBL7835940 | 0.94 | MEN1 (0.35) | KMT2AMEN1BLMADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6159808 | 0.93 | MEN1 (0.34) | KMT2AMEN1BLMADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6159358 | 0.93 | KDM4E (0.37) | KMT2AMEN1BLMADRA2AADRA2B | |
| SCHEMBL6158502 | 0.92 | KMT2A (0.37) | KMT2AMEN1BLMADRA2AADRA2B | |
| SCHEMBL27417173 | 0.92 | KMT2A (0.37) | KMT2AMEN1BLMADRA2AADRA2B | |
| SCHEMBL7858511 | 0.92 | AURKA (0.36) | KMT2AMEN1BLMADRA2AADRA2B | |
| SCHEMBL6158156 | 0.92 | KMT2A (0.40) | KMT2AMEN1BLMADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6158829 | 0.91 | AURKA (0.35) | KMT2AMEN1BLMADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6968001 | 0.91 | KMT2A (0.36) | KMT2AMEN1BLMADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2005-10-26 | — | — | EP | claimed |
| CN-1159312-C | Novel poyrimidine derivatives and process for preparation thereof | ������������ʽ���� | 2004-07-28 | — | — | CN | claimed |
| US-6545008-B1 | Inhibitory activity against gastric acid secretion | YUHAN CORPORATION (KR) | 2003-04-08 | — | — | US | claimed |
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |