Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TXN | P10599 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159808 | 0.99 | MEN1 (0.34) | MEN1BLMKMT2AADRA2AADRA2B | |
| SCHEMBL6158502 | 0.94 | KMT2A (0.37) | MEN1BLMKMT2AADRA2AADRA2B | |
| SCHEMBL6159299 | 0.94 | KMT2A (0.40) | MEN1BLMKMT2AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6160343 | 0.93 | KMT2A (0.36) | MEN1BLMKMT2AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6159666 | 0.93 | KMT2A (0.39) | MEN1BLMKMT2AADRA2AADRA2B | |
| SCHEMBL7836074 | 0.92 | MEN1 (0.35) | MEN1BLMKMT2AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6159137 | 0.91 | MEN1 (0.34) | MEN1BLMKMT2AADRA2AADRA2B | |
| SCHEMBL7831456 | 0.91 | BRD4 (0.36) | MEN1BLMKMT2AADRA2AADRA2B | |
| SCHEMBL7858511 | 0.90 | AURKA (0.36) | MEN1BLMKMT2AADRA2AADRA2B | |
| SCHEMBL7835165 | 0.90 | AURKA (0.36) | MEN1KMT2AAURKAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |