Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158023 | 0.88 | CCKBR (0.66) | CCKBRCYP2D6CYP2C9SCN9A | |
| SCHEMBL6159001 | 0.85 | CCKBR (0.51) | CCKBRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6159328 | 0.83 | CCKBR (0.50) | CCKBRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6161149 | 0.82 | CCKBR (0.86) | CCKBR | |
| SCHEMBL6160058 | 0.78 | CCKBR (0.47) | CCKBRCYP19A1MEN1ALDH1A1HTT | |
| SCHEMBL6160599 | 0.78 | CCKBR (0.47) | CCKBRCYP19A1MEN1ALDH1A1HTT | |
| SCHEMBL6160565 | 0.78 | CCKBR (0.47) | CCKBRCYP19A1MEN1ALDH1A1HTT | |
| SCHEMBL6330927 | 0.78 | CCKBR (0.59) | CCKBRSCN9A | |
| SCHEMBL6338361 | 0.77 | CCKBR (0.44) | CCKBRALDH1A1 | |
| SCHEMBL6159592 | 0.77 | CCKBR (0.73) | CCKBRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |