SCHEMBL615984

SCHEMBL615984

CC(=O)Oc1cc2ccccc2cc1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.69
ALDH1A1 P00352 6/20 0.69
HPGD P15428 4/20 0.69
HSD17B10 Q99714 4/20 0.62
TSHR P16473 3/20 0.62
PTGS1 P23219 2/20 0.62
PTGS2 P35354 2/20 0.62
BLM P54132 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
ESR1 P03372 1/20 0.62
ITGB3 P05106 1/20 0.62
ITGA2B P08514 1/20 0.62
HMGB1 P09429 1/20 0.62
GGT1 P19440 1/20 0.62
NAPRT Q6XQN6 1/20 0.62
CFD P00746 2/20 0.59
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C9 P11712 1/20 0.56
MAPT P10636 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3912777 0.98 KDM4E (0.67) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL536584 0.98 KDM4E (0.67) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8122221 0.85 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8116558 0.85 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL6906339 0.85 CA12 (0.55) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL4345750 0.84 IRAK4 (0.64) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL3912770 0.84 MAPT (0.50) KDM4EALDH1A1HPGDHSD17B10TSHR
Zinc Ion SCHEMBL536583 0.84 MAPT (0.50) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8115471 0.83 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8124639 0.83 KDM4E (0.68) KDM4EALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0261821-A2 Improved polyamide fibres IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-30 EP claimed
EP-1788014-B1 Thermosensitive adhesive composition, method of manufacturing the same and thermosensitive adhesive article RICOH CO LTD (JP) 2016-03-09 EP disclosed
US-8653086-B2 Naphthamides as anticancer agents OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-02-18 US disclosed
US-8653086-B2 Naphthamides as anticancer agents OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-02-18 US disclosed
CN-101463246-B Heat-sensitive adhesive and heat-sensitive adhesive material RICOH CO LTD 2013-10-16 CN disclosed
US-8354359-B2 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH COMPANY, LTD. (JP) 2013-01-15 US disclosed
US-8324405-B2 Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors FIBROGEN, INC. (US) 2012-12-04 US disclosed
CN-101143997-B Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH CO LTD 2012-09-26 CN disclosed
US-8114993-B2 Use of aryl chlorides in palladium-catalyzed C-H bond functionalization THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-02-14 US disclosed
CN-1931948-B Thermosensitive adhesive component, and thermosensitive adhesive label sheet RICOH CO LTD 2011-10-19 CN disclosed
EP-0612628-A1 Thermosensitive recording material using phthalic acid derivatives Ricoh Company, Ltd (JP) 1994-08-31 EP disclosed
US-5324728-A Lipoxygenase inhibiting antiallergens FUJIREBIO INC. (JP) 1994-06-28 US disclosed
US-5306687-A Optical recording media comprising p'-methylphenyl p-chlorobenzoate as thermosensitizers RICOH COMPANY, LTD. (JP) 1994-04-26 US disclosed
EP-0265240-B1 LIQUID-CRYSTALLINE POLYMER POLYPLASTICS CO. LTD. (JP) 1993-08-18 EP disclosed
EP-0492178-A2 Naphthoic acid derivative FUJIREBIO INC. (JP) 1992-07-01 EP disclosed
US-5017304-A Polyesters POLYPLASTICS CO., LTD. (JP) 1991-05-21 US disclosed
EP-0154223-B1 PROCESS FOR THE PREPARATION OF 6-ACETOXY-2-NAPHTHOIC ACID AND OF PURE 6-HYDROXY-2-NAPHTHOIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-19 EP disclosed
EP-0265240-A2 Liquid-crystalline polymer POLYPLASTICS CO. LTD. (JP) 1988-04-27 EP disclosed
US-4618701-A Process for preparing 6-acetoxy-2-naphthoic-acid and pure 6-hydroxy-2-naphthoic acid HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-21 US disclosed
EP-0154223-A2 Process for the preparation of 6-acetoxy-2-naphthoic acid and of pure 6-hydroxy-2-naphthoic acid HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-11 EP disclosed