SCHEMBL6906339

SCHEMBL6906339

CC(=O)Oc1cc2ccccc2cc1OC(C)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.55
CA9 Q16790 1/20 0.55
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 4/20 0.53
BLM P54132 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
TSHR P16473 2/20 0.53
HPGD P15428 2/20 0.53
ESR1 P03372 1/20 0.53
ITGB3 P05106 1/20 0.53
ITGA2B P08514 1/20 0.53
HMGB1 P09429 1/20 0.53
GGT1 P19440 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
HSD17B10 Q99714 1/20 0.53
GAA P10253 2/20 0.53
MAPT P10636 2/20 0.53
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7995114 0.92 TNFSF11 (0.61) CA12CA9KDM4EALDH1A1BLM
SCHEMBL14579661 0.89 TNFSF11 (0.58) CA12CA9KDM4EALDH1A1BLM
SCHEMBL6346568 0.88 KDM4E (0.47) CA12CA9KDM4EALDH1A1BLM
SCHEMBL13133134 0.87 ELANE (0.50) CA12CA9KDM4EALDH1A1BLM
SCHEMBL615984 0.85 KDM4E (0.69) CA12CA9KDM4EALDH1A1BLM
SCHEMBL11631516 0.84 NCEH1 (0.49) CA12CA9KDM4EALDH1A1BLM
SCHEMBL536584 0.83 KDM4E (0.67) CA12CA9KDM4EALDH1A1BLM
SCHEMBL14232433 0.83 NCEH1 (0.64) CA12CA9KDM4EALDH1A1BLM
Zinc Ion SCHEMBL536583 0.83 MAPT (0.50) CA12CA9KDM4EALDH1A1BLM
SCHEMBL3912770 0.83 MAPT (0.50) CA12CA9KDM4EALDH1A1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5583188-A USING TITANIUM, ORGANOALUMINUM, NITROGEN OR OXYGEN HETEROCYCLE CONTAINING CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-12-10 US claimed
EP-3066209-B1 NAPHTHALENE DERIVED CHROMOGENIC ENZYME SUBSTRATES GLYCOSYNTH LTD (GB) 2017-12-06 EP disclosed
CN-103635494-B Alpha-olefin polymerization method 胜亚诺盟股份有限公司 2016-12-14 CN disclosed
US-9353198-B2 Method for polymerizing alpha-olefin SUNALLOMER LTD. (JP) 2016-05-31 US disclosed
CN-103880600-A Synthetic method of 2,3-dihydroxy naphthlene NANTONG BAISHENG CHEMICAL CO LTD 2014-06-25 CN disclosed
US-20140148562-A1 METHOD FOR POLYMERIZING ALPHA-OLEFIN SUNALLOMER LTD. (JP) 2014-05-29 US disclosed
CN-103635494-A Method for polymerizing [alpha]-olefin SUNALLOMER LTD 2014-03-12 CN disclosed
US-6777508-B1 HIGHLY ACTIVE AND HIGHLY STEREOSPECIFIC CATALYSTS FOR THE POLYMERIZATION OF PROPYLENE AND HIGHER OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-08-17 US disclosed
EP-0601496-B2 Process for the preparation of olefin polymer MITSUI CHEMICALS INC (JP) 2001-06-27 EP disclosed
US-6194342-B1 COMPRISING REACTION PRODUCT OF ALUMINUM ALKYL COMPOUND, A SILICON COMPOUND CONTAINING ONE SI--OR OR SI--OCOR OR SI--NR2 BOND, R BEING HYDROCARBYL RADICAL, A SOLID COMPRISING AS SUPPORT A MAGNESIUM DIHALIDE AND A TITANIUM HALIDE MONTELL TECHNOLOGY COMPANY BV (NL) 2001-02-27 US disclosed
EP-0045977-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montedison S.p.A. (IT) 1987-01-07 EP disclosed
EP-0086645-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-24 EP disclosed
EP-0179303-A1 Catalysts for the polymerization of olefins Himont Incorporated (US) 1986-04-30 EP disclosed
EP-0125911-A1 Process for production of olefin polymer or copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-11-21 EP disclosed
US-4473660-A COORDINATION CATALYST-CONTAINING ALKYL-ALUMINUM COMPOUND, ELECTRON DONOR, TITANIUM COMPOUND AND ESTER ON MAGNESIUM HALIDE SUPPORT MONTEDISON S.P.A. (IT) 1984-09-25 US disclosed
EP-0086645-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed
EP-0086644-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed
EP-0086643-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed
EP-0086472-A2 Catalyst for the polymerization of olefins Montedison S.p.A. (IT) 1983-08-24 EP disclosed
EP-0045977-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1982-02-17 EP disclosed