SCHEMBL6159937

SCHEMBL6159937

CCCCCCCC/C=C\CCCCCCCCOC(=O)NC(=O)OC(Cc1ccncc1)c1nc(C(C)C)c(Sc2cc(Cl)cc(Cl)c2)[nH]1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 2/20 0.32
LPAR1 Q92633 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6159792 0.96 NPC1 (0.30)
SCHEMBL6160630 0.96 NPC1 (0.30)
SCHEMBL6161865 0.96 NPC1 (0.30)
SCHEMBL6160382 0.91 LPAR3 (0.38) LPAR3LPAR1FAAH
SCHEMBL6160378 0.91 LPAR3 (0.38) LPAR3LPAR1FAAH
SCHEMBL6161223 0.86 HPGD (0.33) LPAR3LPAR1
SCHEMBL6168629 0.86 HPGD (0.33) LPAR3LPAR1
SCHEMBL6166945 0.86 HPGD (0.33) LPAR3LPAR1
SCHEMBL6162172 0.86 HPGD (0.33) LPAR3LPAR1
SCHEMBL6162360 0.86 HPGD (0.33) LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893442-B1 LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES SHIONOGI & CO (JP) 2005-01-12 EP disclosed