Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159792 | 1.00 | NPC1 (0.30) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6161865 | 1.00 | NPC1 (0.30) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6159937 | 0.96 | LPAR3 (0.32) | — | |
| SCHEMBL6160994 | 0.91 | KDM4E (0.32) | L3MBTL1 | |
| SCHEMBL6166945 | 0.90 | HPGD (0.33) | HPGD | |
| SCHEMBL6161223 | 0.90 | HPGD (0.33) | HPGD | |
| SCHEMBL6168629 | 0.90 | HPGD (0.33) | HPGD | |
| SCHEMBL8009855 | 0.90 | HPGD (0.33) | HPGD | |
| SCHEMBL6162172 | 0.90 | HPGD (0.33) | HPGD | |
| SCHEMBL6162360 | 0.90 | HPGD (0.33) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |