Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 9/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160205 | 1.00 | BCHE (0.67) | BCHEACHETRPV1ALDH1A1MAPT | |
| SCHEMBL6158891 | 0.82 | GAA (0.55) | BCHEACHE | |
| SCHEMBL6158887 | 0.82 | GAA (0.55) | BCHEACHE | |
| SCHEMBL9029585 | 0.80 | TRPV1 (0.72) | BCHEACHETRPV1ALDH1A1 | |
| SCHEMBL9029586 | 0.80 | TRPV1 (0.72) | BCHEACHETRPV1ALDH1A1 | |
| SCHEMBL9041758 | 0.80 | TRPV1 (0.76) | BCHEACHETRPV1ALDH1A1 | |
| SCHEMBL9041751 | 0.80 | TRPV1 (0.76) | BCHEACHETRPV1ALDH1A1 | |
| SCHEMBL5029885 | 0.80 | TRPV1 (0.87) | BCHEACHETRPV1ALDH1A1 | |
| SCHEMBL2123698 | 0.80 | TRPV1 (0.87) | BCHEACHETRPV1ALDH1A1 | |
| SCHEMBL2123701 | 0.80 | TRPV1 (0.87) | BCHEACHETRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |