Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158887 | 1.00 | GAA (0.55) | GAAMEN1KMT2ATSHRMCHR1 | |
| SCHEMBL6160199 | 0.82 | HRH3 (0.49) | GAAMEN1KMT2AMCHR1 | |
| SCHEMBL6160208 | 0.82 | HRH3 (0.49) | GAAMEN1KMT2AMCHR1 | |
| SCHEMBL6160195 | 0.82 | BCHE (0.67) | BCHEACHE | |
| SCHEMBL6160205 | 0.82 | BCHE (0.67) | BCHEACHE | |
| SCHEMBL6162831 | 0.79 | CCR3 (0.53) | MEN1KMT2ATSHR | |
| SCHEMBL6162841 | 0.79 | CCR3 (0.53) | MEN1KMT2ATSHR | |
| SCHEMBL6160743 | 0.79 | GAA (0.47) | GAAMEN1KMT2ATSHRAPP | |
| SCHEMBL6160732 | 0.79 | GAA (0.47) | GAAMEN1KMT2ATSHRAPP | |
| SCHEMBL6162033 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |