Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.43 |
| ▸ | DRD2 | P14416 | 11/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157715 | 0.88 | DRD3 (0.44) | DRD3DRD2HTR1DHTR1BS1PR3 | |
| SCHEMBL6156737 | 0.80 | HTR1D (0.51) | DRD3DRD2HTR1DHTR1BHTR2C | |
| SCHEMBL6156696 | 0.79 | MCHR1 (0.40) | DRD3DRD2HTR1DHTR1BCYP3A4 | |
| SCHEMBL6159141 | 0.77 | DRD2 (0.44) | DRD3DRD2S1PR3CYP3A4CYP2C8 | |
| SCHEMBL6158197 | 0.75 | SPHK1 (0.35) | DRD3DRD2HTR1DHTR1B | |
| SCHEMBL5684871 | 0.73 | HTR1D (0.36) | DRD3DRD2HTR1DHTR1BS1PR3 | |
| SCHEMBL11215179 | 0.72 | CYP3A4 (0.56) | DRD3DRD2S1PR3CYP3A4CYP2C8 | |
| SCHEMBL6157524 | 0.70 | SPHK1 (0.35) | DRD3DRD2HTR1DHTR1BHTR2C | |
| SCHEMBL5684003 | 0.69 | HTR1D (0.36) | DRD3DRD2HTR1DHTR1BS1PR1 | |
| SCHEMBL5683988 | 0.69 | HTR1D (0.36) | DRD3DRD2HTR1DHTR1BS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191008-B1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6746728-B1 | SUPERIOR LIQUID CRYSTALLINITY AND CO-SOLUBILITY WITH CURRENTLY USED LIQUID CRYSTAL COMPOUNDS; TEMPERATURE RANGE OVER WHICH LIQUID CRYSTALLINITY IS SHOWN IS BROAD; THRESHOLD VOLTAGE IS LOW; CAPABLE OF HIGH SPEED RESPONSE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1191008-A1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-03-27 | — | — | EP | disclosed |
| JP-2001039906-A | COMPOUND BEARING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL CONTAINING THE SAME | DAINIPPON INK & CHEM INC | 2001-02-13 | — | — | JP | disclosed |