Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.31 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12480274 | 0.89 | PARP1 (0.38) | DHODHCDC7CCNCCDK8CHEK2 | |
| SCHEMBL3065165 | 0.83 | PARP1 (0.46) | CDC7CCNCCDK8MAP2K4TTK | |
| Hydrochloric Acid SCHEMBL12469361 | 0.82 | MAP2K4 (0.45) | CDC7CCNCCDK8MAP2K4TTK | |
| SCHEMBL751010 | 0.82 | MKNK1 (0.42) | MKNK1MKNK2MAP4K4MAP2K4CHEK2 | |
| SCHEMBL2513559 | 0.80 | ALOX15 (0.36) | DHODHMAP2K4SMN1; SMN2MAPK1MAPKAPK3 | |
| SCHEMBL733156 | 0.76 | DHODH (0.49) | DHODHMAP2K4SMN1; SMN2MAPK1MAPKAPK3 | |
| SCHEMBL6160731 | 0.75 | USP2 (0.34) | SMN1; SMN2 | |
| SCHEMBL2513525 | 0.75 | EGFR (0.47) | MKNK1MKNK2 | |
| Carbamic Acid SCHEMBL27894860 | 0.73 | CYP1A2 (0.45) | DHODHCHEK2PARP1MAPK1 | |
| SCHEMBL27676654 | 0.72 | ATM (0.41) | MAP2K4SMN1; SMN2MAPK1MAPKAPK3MAPK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |