Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | TPMT | P51580 | 3/20 | 0.48 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Dichloroisonicotinic Acid SCHEMBL56204 | 0.86 | TPMT (0.56) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL11071500 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27673705 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27673665 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27653662 | 0.84 | TSHR (0.58) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL2264628 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL7828838 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27653711 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27653766 | 0.84 | TPMT (0.54) | TTRTPMTHCAR1TSHRALOX15 | |
| Citrazinic Acid SCHEMBL185046 | 0.84 | TSHR (0.56) | TTRTPMTHCAR1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7173012-A | — | — | None | — | — | JP | disclosed |
| JP-8208613-A | — | — | None | — | — | JP | disclosed |
| EP-2178858-B1 | NOVEL HETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LTD (IE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2009015897-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2009-02-05 | — | — | WO | disclosed |
| EP-1016661-B1 | 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AS AGRICULTURAL CHEMICALS | DAINIPPON INK & CHEMICALS (JP) | 2005-08-03 | — | — | EP | disclosed |
| CN-1120155-C | 2,6-dichloro-4-pyridinemethanol derivatives and agricultural chemicals | DAINIPPON INK & CHEMICALS (JP) | 2003-09-03 | — | — | CN | disclosed |
| US-6281231-B1 | 2,6-dichloro-4-pyridinemethanol derivatives and agricultural chemicals | DAINIPPON INK AND CHEMICAL, INC. (JP) | 2001-08-28 | — | — | US | disclosed |
| CN-1270581-A | 2,6-dichloro-4-pyridinemethanol derivatives and agricultural chemicals | DAINIPPON INK & CHEMICALS (US) | 2000-10-18 | — | — | CN | disclosed |
| EP-1016661-A1 | 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AND AGRICULTURAL CHEMICALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-07-05 | — | — | EP | disclosed |
| JP-H08208613-A | 2-CHLORO-6-HYDROXYISONICOTINIC ACID DERIVATIVE AND PLANT DISEASE INJURY-CONTROLLING AGENT | DAINIPPON INK & CHEM INC | 1996-08-13 | — | — | JP | disclosed |
| JP-H07173012-A | CONTROLLING AGENT AGAINST PLANT DISEASE INJURY | DAINIPPON INK & CHEM INC | 1995-07-11 | — | — | JP | disclosed |