SCHEMBL6160853

SCHEMBL6160853

Cc1cc(C)c(-c2nc(C(=O)Nc3cccc(CC(=O)O)c3)c(COC34CC5CC(CC(C5)C3)C4)[nH]2)c(C)c1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6159755 0.89 CCKBR (0.68) CCKBR
SCHEMBL6160081 0.87
SCHEMBL6160236 0.82 CCKBR (0.79) CCKBR
SCHEMBL6160431 0.82 CCKBR (0.79) CCKBR
SCHEMBL6160142 0.82 CCKBR (0.58) CCKBR
SCHEMBL6159494 0.78 CCKBR (0.68) CCKBR
SCHEMBL6159330 0.78 CCKBR (0.70) CCKBR
SCHEMBL6160341 0.76
SCHEMBL6158857 0.76 CCKBR (0.59) CCKBR
SCHEMBL6159882 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1178969-B1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS BLACK JAMES FOUNDATION (GB) 2005-07-13 EP disclosed
US-6479531-B1 Gastrin and cholecystokinin receptor ligands JAMES BLACK FOUNDATION LIMITED (GB) 2002-11-12 US disclosed
EP-1178969-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2002-02-13 EP disclosed
WO-2000027823-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2000-05-18 WO disclosed