Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160412 | 0.90 | CYP19A1 (0.40) | — | |
| SCHEMBL7085195 | 0.86 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL6161248 | 0.85 | — | — | |
| SCHEMBL7688989 | 0.83 | KDM4E (0.34) | P2RX7 | |
| SCHEMBL6158866 | 0.79 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL6164287 | 0.77 | EPHX2 (0.34) | — | |
| SCHEMBL6159867 | 0.77 | POLB (0.35) | — | |
| SCHEMBL6159862 | 0.77 | POLB (0.35) | — | |
| SCHEMBL7533804 | 0.75 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL6159838 | 0.74 | PPARG (0.39) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |