Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159783 | 0.80 | SLC9A1 (0.39) | RAB9AMAPTSTAT1NPSR1POLB | |
| SCHEMBL6158738 | 0.76 | EPHX2 (0.40) | — | |
| SCHEMBL8963796 | 0.68 | SLC9A1 (0.50) | RAB9ANPSR1NPC1SLC9A1SMN1; SMN2 | |
| SCHEMBL6157631 | 0.67 | — | — | |
| SCHEMBL21572853 | 0.66 | TDP1 (0.58) | RAB9AMAPTSTAT1NPSR1POLB | |
| SCHEMBL8963836 | 0.65 | SLC9A1 (0.50) | RAB9ANPSR1NPC1SLC9A1SMN1; SMN2 | |
| SCHEMBL5554927 | 0.65 | KDM4E (0.48) | RAB9AMAPTNPSR1POLBKMT2A | |
| SCHEMBL20201222 | 0.65 | POLB (0.57) | RAB9AMAPTPOLBNPC1KMT2A | |
| SCHEMBL25541336 | 0.65 | TDP1 (0.51) | RAB9AMAPTSTAT1NPSR1NPC1 | |
| SCHEMBL19928470 | 0.64 | TDP1 (0.54) | RAB9AMAPTSTAT1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |