Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
| ▸ | LDLR | P01130 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161435 | 0.88 | CCKBR (0.50) | CCKBRLDLRCYP2D6CYP2C9 | |
| SCHEMBL6162743 | 0.86 | CCKBR (0.49) | CCKBR | |
| SCHEMBL6158243 | 0.85 | CCKBR (0.57) | CCKBR | |
| SCHEMBL6158987 | 0.84 | LDLR (0.49) | LDLR | |
| SCHEMBL6158100 | 0.83 | CCKBR (0.67) | CCKBR | |
| SCHEMBL6158018 | 0.83 | CCKBR (0.67) | CCKBR | |
| SCHEMBL6168427 | 0.81 | CCKBR (0.74) | CCKBR | |
| SCHEMBL6161021 | 0.81 | CCKBR (0.74) | CCKBR | |
| SCHEMBL6159718 | 0.81 | CCKBR (0.74) | CCKBR | |
| SCHEMBL6159223 | 0.79 | CCKBR (0.60) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |