Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161953 | 0.85 | — | — | |
| SCHEMBL6159302 | 0.83 | CNR1 (0.46) | — | |
| SCHEMBL6160991 | 0.79 | CHEK2 (0.41) | — | |
| SCHEMBL6159589 | 0.76 | ACMSD (0.40) | ACMSD | |
| SCHEMBL31149603 | 0.75 | BRS3 (0.41) | BRS3KDM5AKDM5B | |
| SCHEMBL31149208 | 0.74 | FFAR1 (0.43) | BRS3 | |
| SCHEMBL31149588 | 0.72 | NOTUM (0.34) | BRS3KDM5AKDM5B | |
| SCHEMBL31149643 | 0.72 | BRS3 (0.37) | BRS3KDM5AKDM5B | |
| SCHEMBL6161229 | 0.72 | — | — | |
| SCHEMBL6159443 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |