Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158876 | 0.84 | CCKBR (0.64) | CCKBRHIF1AEPAS1EPHX2 | |
| SCHEMBL6160606 | 0.83 | CCKBR (0.52) | CCKBRHIF1AEPAS1EPHX2 | |
| SCHEMBL6161342 | 0.82 | CCKBR (0.51) | CCKBREPHX2 | |
| SCHEMBL6161003 | 0.77 | CCKBR (0.73) | CCKBR | |
| SCHEMBL6064529 | 0.77 | CCKBR (0.59) | CCKBRHIF1AEPAS1EPHX2 | |
| SCHEMBL6065049 | 0.75 | CCKBR (0.63) | CCKBRHIF1AEPAS1EPHX2 | |
| SCHEMBL6159631 | 0.75 | CCKBR (0.53) | CCKBR | |
| SCHEMBL6065151 | 0.74 | CCKBR (0.57) | CCKBREPHX2 | |
| SCHEMBL6065076 | 0.74 | CCKBR (0.64) | CCKBREPHX2 | |
| SCHEMBL6064921 | 0.74 | CCKBR (0.64) | CCKBREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |