Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.66 |
| ▸ | ALPI | P09923 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | XIAP | P98170 | 1/20 | 0.66 |
| ▸ | GRB2 | P62993 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | TPH1 | P17752 | 3/20 | 0.54 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.54 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180272 | 0.92 | SLC7A5 (0.78) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL93494 | 0.92 | SLC7A5 (0.78) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL414363 | 0.92 | SLC7A5 (0.78) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL1796036 | 0.92 | SLC7A5 (0.78) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL93495 | 0.92 | SLC7A5 (0.78) | SLC7A5ALPIPKMPTGS1XIAP | |
| Benzene SCHEMBL27761112 | 0.90 | SLC7A5 (0.70) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL3047281 | 0.90 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL3050654 | 0.90 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| D-Phenylalanine SCHEMBL3054019 | 0.90 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL7450242 | 0.90 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |