SCHEMBL414363

SCHEMBL414363

N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O.N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.78
PTGS1 P23219 2/20 0.78
ALPI P09923 1/20 0.78
PKM P14618 1/20 0.78
XIAP P98170 1/20 0.78
SRR Q9GZT4 2/20 0.62
PSAT1 Q9Y617 2/20 0.62
TPH1 P17752 4/20 0.60
GRIA2 P42262 1/20 0.57
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
KDM4E B2RXH2 1/20 0.56
USP2 O75604 1/20 0.56
EGFR P00533 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
ALOX15 P16050 1/20 0.56
HTR2A P28223 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93495 1.00 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1796036 1.00 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL93494 1.00 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL180272 1.00 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL3695982 0.98 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL7567510 0.98 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL6888643 0.98 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Benzene SCHEMBL27761112 0.95 SLC7A5 (0.70) SLC7A5PTGS1ALPIPKMXIAP
D-Phenylalanine SCHEMBL23044028 0.94 SLC7A5 (0.88) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL22401402 0.94 SLC7A5 (0.88) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210030918-A1 COATING OF FIBERS WITH DIPEPTIDE NANOSTRUCTURES USING ULTRASONIC CAVITATION RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2021-02-04 US claimed
EP-2089418-B1 FORMATION OF ORGANIC NANOSTRUCTURE ARRAY UNIV RAMOT (IL) 2016-11-09 EP claimed
EP-2961433-A1 PEPTIDE-BASED HYDROGEL PARTICLES AND USES THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2016-01-06 EP claimed
EP-1781310-B1 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME UNIV RAMOT (IL) 2015-10-14 EP claimed
US-9074095-B2 Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2015-07-07 US claimed
US-8927689-B2 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-01-06 US claimed
WO-2014132262-A1 PEPTIDE-BASED HYDROGEL PARTICLES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-09-04 WO claimed
US-8796023-B2 Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-08-05 US claimed
EP-2575909-A1 MALLEABLE HYDROGEL HYBRIDS MADE OF SELF-ASSEMBLED PEPTIDES AND BIOCOMPATIBLE POLYMERS AND USES THEREOF Ramot at Tel Aviv University, Ltd. (IL) 2013-04-10 EP claimed
US-20130079421-A1 MALLEABLE HYDROGEL HYBRIDS MADE OF SELF-ASSEMBLED PEPTIDES AND BIOCOMPATIBLE POLYMERS AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2013-03-28 US claimed
US-7504383-B2 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-03-17 US claimed
US-7491699-B2 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. 2009-02-17 US claimed
EP-1973928-A2 SELF-ASSEMBLED FMOC-FF HYDROGELS Ramot at Tel-Aviv University Ltd. (IL) 2008-10-01 EP claimed
US-20080009434-A1 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2008-01-10 US claimed
EP-1781310-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME Ramot at Tel Aviv University Ltd. (IL) 2007-05-09 EP claimed
WO-2007043048-A2 SELF-ASSEMBLED FMOC-FF HYDROGELS RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2007-04-19 WO claimed
US-20060079455-A1 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-04-13 US claimed
US-20060079454-A1 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-04-13 US claimed
WO-2006027780-A2 PEPTIDE NANOSTRUCTURES CONTAINING END-CAPPING MODIFIED PEPTIDES AND METHODS OF GENERATING AND USING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-03-16 WO claimed
WO-2006013552-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-02-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210030918-A1 COATING OF FIBERS WITH DIPEPTIDE NANOSTRUCTURES USING ULTRASONIC CAVITATION VIP, NPPA, IAPP SLC7A5 2842/4885PTGS1 4499/4885ALPI 2386/4885
US-20080009434-A1 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody DNPEP, LNPEP, ANPEP SLC7A5 17/4885PTGS1 4835/4885ALPI 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.