Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.53 |
| ▸ | CTSK | P43235 | 9/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164417 | 0.89 | PTPN1 (0.59) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6163926 | 0.85 | USP30 (0.57) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6161572 | 0.83 | USP30 (0.45) | USP30F10ITGB3ITGB1ITGAV | |
| SCHEMBL6166259 | 0.80 | PTPN1 (0.47) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL2999836 | 0.79 | CTSS (0.69) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL2999840 | 0.79 | CTSS (0.69) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6163562 | 0.79 | USP30 (0.55) | CTSSCTSKCTSBCTSLUSP30 | |
| SCHEMBL25419654 | 0.79 | CTSS (0.58) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6164303 | 0.79 | CTSS (0.58) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6166435 | 0.78 | USP30 (0.59) | USP30F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |