SCHEMBL6161573

SCHEMBL6161573

C[CH]C(=O)NCCCCCCC

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.68
ZDHHC2 Q9UIJ5 3/20 0.68
EPHX1 P07099 10/20 0.61
CASP2 P42575 1/20 0.55
NAAA Q02083 1/20 0.52
EGFR P00533 1/20 0.51
FAAH O00519 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6164190 1.00 ZDHHC20 (0.68) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL11481896 1.00 ZDHHC20 (0.68) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL6162875 1.00 ZDHHC20 (0.68) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL6163158 1.00 ZDHHC20 (0.68) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL6164916 1.00 ZDHHC20 (0.68) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL6163635 0.98 ZDHHC20 (0.64) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL486681 0.91
SCHEMBL6131120 0.84 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL444526 0.84 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2NAAA
SCHEMBL2530353 0.84 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5334716-A Preventing testosteron 5a-reductase mediated diseases; alopecia, acne, prostatism FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-08-02 US claimed
EP-1055712-B1 Aqueous ink for ink jet recording MITSUI CHEMICALS INC (JP) 2005-02-16 EP disclosed
EP-1055712-A2 Aqueous ink for ink jet recording Mitsui Chemicals, Inc. (JP) 2000-11-29 EP disclosed
EP-0519353-B1 Indolizin derivatives, process for their preparation and pharmaceutical composition containing them FUJISAWA PHARMACEUTICAL CO (JP) 2000-08-16 EP disclosed
EP-0717742-B1 PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 1998-11-11 EP disclosed
US-5780633-A Process for the preparation of indolizine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-14 US disclosed
EP-0717742-A1 PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-06-26 EP disclosed
WO-1995007279-A2 PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-03-16 WO disclosed
US-5334716-A Preventing testosteron 5a-reductase mediated diseases; alopecia, acne, prostatism FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-08-02 US disclosed
EP-0519353-A2 Indolizin derivatives, process for their preparation and pharmaceutical composition containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-12-23 EP disclosed