Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162878 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL6164920 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL6164193 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL5543478 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL6163638 | 0.98 | CASP2 (0.63) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL351990 | 0.91 | — | — | |
| SCHEMBL14370358 | 0.84 | CASP2 (0.75) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL14890990 | 0.84 | CASP2 (0.75) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL9548566 | 0.84 | CASP2 (0.75) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL11923736 | 0.84 | CASP2 (0.75) | CASP2NAAAEPHX1ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334716-A | Preventing testosteron 5a-reductase mediated diseases; alopecia, acne, prostatism | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | claimed |
| EP-1055712-B1 | Aqueous ink for ink jet recording | MITSUI CHEMICALS INC (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1055712-A2 | Aqueous ink for ink jet recording | Mitsui Chemicals, Inc. (JP) | 2000-11-29 | — | — | EP | disclosed |
| EP-0519353-B1 | Indolizin derivatives, process for their preparation and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0717742-B1 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5780633-A | Process for the preparation of indolizine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0717742-A1 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007279-A2 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |
| US-5334716-A | Preventing testosteron 5a-reductase mediated diseases; alopecia, acne, prostatism | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |