Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161589 | 1.00 | MEN1 (0.45) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6163815 | 0.93 | MEN1 (0.47) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6163811 | 0.93 | MEN1 (0.47) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6163376 | 0.91 | MEN1 (0.46) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6163388 | 0.91 | MEN1 (0.46) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6162200 | 0.91 | MEN1 (0.45) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6162193 | 0.91 | MEN1 (0.45) | MEN1KMT2ATACR1ITGB2ICAM1 | |
| SCHEMBL6160909 | 0.88 | CTSL (0.50) | MEN1KMT2ATACR1CTSLCTSS | |
| SCHEMBL6166772 | 0.88 | MEN1 (0.47) | MEN1KMT2ATACR1CTSLCTSS | |
| SCHEMBL6166766 | 0.88 | MEN1 (0.47) | MEN1KMT2ATACR1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |