Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 16/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.56 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163603 | 1.00 | CALCRL (0.59) | CALCRLCYP3A4RAMP1GHSRHSD11B1 | |
| Hydrochloric Acid SCHEMBL6160811 | 0.99 | CALCRL (0.58) | CALCRLCYP3A4RAMP1GHSRHSD11B1 | |
| Hydrochloric Acid SCHEMBL6161941 | 0.99 | CALCRL (0.58) | CALCRLCYP3A4RAMP1GHSRHSD11B1 | |
| SCHEMBL6162042 | 0.90 | CALCRL (0.58) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6161820 | 0.90 | CALCRL (0.58) | CALCRLCYP3A4RAMP1HSD11B1 | |
| Hydrochloric Acid SCHEMBL6160050 | 0.90 | CALCRL (0.54) | CALCRLCYP3A4RAMP1HSD11B1 | |
| Hydrochloric Acid SCHEMBL6161739 | 0.90 | CALCRL (0.54) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6161677 | 0.89 | CALCRL (0.57) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6162040 | 0.88 | CALCRL (0.52) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6162035 | 0.88 | CALCRL (0.52) | CALCRLCYP3A4RAMP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721455-B9 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2005-04-20 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0721455-B1 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2002-12-11 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |