Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161645 | 1.00 | GHSR (0.46) | GHSRSOS1CYP51A1OPRM1MMP3 | |
| Hydrochloric Acid SCHEMBL6161099 | 0.99 | GHSR (0.46) | GHSRSOS1CYP51A1OPRM1MMP3 | |
| Hydrochloric Acid SCHEMBL6161103 | 0.99 | GHSR (0.46) | GHSRSOS1CYP51A1OPRM1MMP3 | |
| SCHEMBL6160307 | 0.95 | GHSR (0.44) | GHSRSOS1CYP51A1OPRM1HSD11B1 | |
| SCHEMBL6160306 | 0.95 | GHSR (0.44) | GHSRSOS1CYP51A1OPRM1HSD11B1 | |
| Hydrochloric Acid SCHEMBL6163645 | 0.94 | GHSR (0.44) | GHSRSOS1CYP51A1OPRM1HSD11B1 | |
| Hydrochloric Acid SCHEMBL6163650 | 0.94 | GHSR (0.44) | GHSRSOS1CYP51A1OPRM1HSD11B1 | |
| SCHEMBL6163394 | 0.94 | GHSR (0.46) | GHSRCYP51A1OPRM1MMP3ITGB2 | |
| SCHEMBL6163389 | 0.94 | GHSR (0.46) | GHSRCYP51A1OPRM1MMP3ITGB2 | |
| Hydrochloric Acid SCHEMBL6162120 | 0.93 | GHSR (0.46) | GHSRCYP51A1OPRM1MMP3ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |